Pacific Brain Tumor Center

Overview

Comprehensive Brain Tumor Care

At the Pacific Brain Tumor Center, we provide comprehensive care for patients with all types of brain tumors including benign and malignant brain tumors, skull base tumors, and metastatic brain tumors that arise from cancers elsewhere in the body.

Our multidisciplinary team of brain tumor experts—including neurosurgeons, ENT (head & neck – otolaryngology) surgeons, neuro-ophthalmologists, and neuro-oncologists—offers personalized precision treatment for each patient’s diagnosis. We treat even the most complex cases using advanced, minimally invasive brain tumor surgery techniques, including keyhole surgery and endoscopic approaches, to safely and effectively remove brain tumors while reducing recovery time.

With a compassionate, patient-first approach, we combine advanced imaging, surgical navigation tools, and targeted therapies to deliver effective treatment while restoring quality of life. We offer expert second opinions—in person or via telemedicine—for individuals already diagnosed, including patients in Greater Los Angeles, across the United States, and internationally.

Conditions & Treatments

Brain Tumors Treated by Our Specialists.

Our board-certified surgeons and specialists diagnose and treat all types of benign and malignant brain tumors.

Treatments and Procedures

With expertise in minimally invasive keyhole and endoscopic surgery, advanced brain cancer treatments and clinical trials, and stereotactic radiation therapy, our brain tumor specialists create personalized treatment plans based on each patient’s diagnosis, tumor type, and overall health—to help achieve the best possible outcomes.

Services

Comprehensive Brain Tumor Services

Supportive Care Clinic

Our Supportive Care Clinic focuses on enhancing the quality of life for patients undergoing treatment for brain and skull base tumors. We provide comprehensive services, including symptom management and emotional support, tailored to address the unique challenges faced during and after treatment. Our multidisciplinary team collaborates to ensure that both patients and their families receive holistic care throughout the treatment journey.​

Genomic Tumor Sequencing

We provide comprehensive tumor sequencing for surgically removed tumors. This includes options for whole genome analysis and tumor marker profiling, helping us personalize treatment based on each patient’s biology. We also collaborate with outside labs and institutions to facilitate advanced sequencing when needed.

Clinical Trials & Research

Brain Tumor Clinical Trials

At the Pacific Brain Tumor Center, we are committed to advancing care for brain and skull base tumors through clinical trials and ongoing research. We offer trials for patients with high-grade gliomas, metastatic brain cancers, and skull base tumors, often combining standard treatments with novel therapies.

Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors

This is a first-in-human, Phase 1/2 open-label, multicenter, dose-escalation, safety, PK, and biomarker study of PBI-200 in subjects with NTRK-fusion-positive advanced or metastatic solid tumors.

Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies

The objective of this expanded access program is to provide ulixertinib (BVD-523) for compassionate use in advanced cancer patients with MAPK pathway-altered solid tumor(s), including but not limited to KRAS, NRAS, HRAS, BRAF, MEK, and ERK mutations who have incomplete response to or have exhausted available therapies.

A First in Human Study of AdAPT-001 in Subjects With Refractory Solid Tumors (BETA-PRIME)

This is the first clinical trial of AdAPT-001 for the treatment of cancer. AdAPT-001 is an oncolytic virus that is injected directly into the tumor. The purpose of this study is to find out the highest dose of AdAPT-001 that is safe and tolerable. This is the first step in studying whether it can be used to treat others with cancer in the future.

Patient Support

Support That Goes Beyond Your Appointment

Details regarding insurance coverage and billing information are available at Providence.org.

Locations

Locations Serving Brain Tumor Patients

Saint John’s Health Center

2121 Santa Monica Blvd
Santa Monica, CA 90404

PNI-South Bay

5215 Torrance Blvd #300
Torrance, CA 90503

PNI-Santa Monica

2125 Arizona Ave
Santa Monica, CA 90404

Saint Joseph Medical Center – Neuro Clinic

501 South Buena Vista Street
Burbank, CA 91505

Disney Family Cancer Center

181 S Buena Vista St
Burbank, CA 91505

Saint Jude Medical Building

2151 N. Harbor Blvd
Fullerton, CA 92835

Saint Joseph Hospital Medical Building

1000 W La Veta Ave
Floor 1
Orange, CA 92868
Contact Us

Saint John’s Health Center
2121 Santa Monica Blvd,
Garden Level, Santa Monica, CA 90404
310-829-8265

PNI-South Bay
5215 Torrance Blvd #300
Torrance, CA 90503
424-212-5361

PNI-Santa Monica
2125 Arizona Ave, 2nd Floor
Santa Monica, CA 90404
310-582-7450

Saint Joseph Medical Center – Neuro Clinic
501 S Buena Vista St
Burbank, CA 91505
818-847-6049

Disney Family Cancer Center
181 S. Buena Vista St
Burbank, CA 91505
818-847-6049

Saint Jude Medical Building
2151 N. Harbor Blvd #3100
Fullerton, CA 92835
714-446-5830

Saint Joseph Hospital Medical Building
1000 W. La Veta Ave
Orange, CA 92868
714-734-6294