Multiple Sclerosis & Related Disorders
Compassionate expert treatment, backed by experience
At the Multiple Sclerosis Clinic at Pacific Neuroscience Institute (PNI), we specialize in the diagnosis, treatment, and ongoing management of multiple sclerosis (MS) and related demyelinating diseases of the central nervous system.
Directed by Barbara S. Giesser, MD, an internationally recognized MS specialist with over 40 years of experience, our clinic offers compassionate, whole-person care that integrates leading-edge therapies with lifestyle interventions and rehabilitation.
Our team is proud to be recognized by the National Multiple Sclerosis Society as a Center for Comprehensive MS Care, a distinction that highlights our commitment to coordinated, expert-led, and patient-centered treatment.

PNI offers world-class care with on-site specialists in Neuro-ophthalmology, Neurosurgery, Endocrinology, and ENT. When needed, we also coordinate referrals to other specialties such as Urology, Urogynecology, Psychiatry, and Internal Medicine to ensure comprehensive care.
Whether you’re newly diagnosed, seeking a second opinion, or managing a long-term course of MS, our multidisciplinary approach is designed to empower you and improve your quality of life—every step of the way.
Conditions Treated by Our Specialists
- Multiple Sclerosis (Relapsing-Remitting, Primary Progressive, Secondary Progressive)
- Radiologically Isolated Syndrome
- Neuromyelitis Optica/MOGAD
- Transverse Myelitis
- Optic Neuritis
Treatments & Procedures for MS
While there is currently no cure for Multiple Sclerosis (MS), it is an eminently treatable condition. Advances in medical therapies and supportive care have significantly improved the ability to manage symptoms, reduce relapses, and slow disease progression. We offer a comprehensive, personalized approach to treatment that empowers patients to live full and active lives.
- Disease‑Modifying Therapies (DMTs)
Over 20 FDA‑approved therapies aimed at reducing relapse rate and slowing progression. - Infusion Therapy
Safe in-clinic administration of biologic therapies on site. - Symptom Management
Fatigue, spasticity, pain, bladder/bowel/sexual dysfunction, vision issues, cognitive changes—managed through medications, rehabilitation, assistive devices, and complementary approaches. - Rehabilitation & Exercise Therapy
Using in house and community resources to provide tailored plans with speech pathology, occupational, and physical therapists with physical activity coaching and equipment adaptation. - Lifestyle-Based Interventions
Dietary recommendations, exercise planning, heat sensitivity strategies, and other strategies to improve brain health, reflecting evidence-based benefit of lifestyle interventions.
Multiple Sclerosis Diagnostics & Services
- Comprehensive neurological evaluation & diagnostic workup
- Second opinions for patients in Southern California (in-person only)
- Telemedicine and in-person appointments
- Multidisciplinary care coordination
- Patient and caregiver education
- Cognitive health & neuropsychology support
- Wellness counseling and lifestyle recommendations integration
Support That Goes Beyond Your Appointment
Brain Wellness & Lifestyle Program at PNI
Learn how to preserve memory and brain function with the Brain Wellness & Lifestyle Program at Pacific Neuroscience Institute. We offer in-person and virtual courses led by brain health experts
Details regarding insurance coverage, and billing information are available at Providence.org.
Locations Serving Multiple Sclerosis Patients

Request an Appointment
Contact Information
PNI-Santa Monica
2125 Arizona Ave, 2nd Floor
Santa Monica, CA 90404
310-582-7433