Brain & skull base tumors
comprise a wide spectrum
of tumor types


We treat all types of brain tumors with leading-edge technology and novel therapeutic approaches.

Most symptomatic brain tumors and tumors of the skull base warrant surgical removal. Brain tumors that are malignant or cancerous typically require additional treatments such as chemotherapy, immunotherapy or focused radiation. Fortunately, most brain tumors can now be removed through one of several minimally invasive keyhole routes depending upon tumor location and size.

At Pacific BTC, we have one of the world’s largest experiences in minimally invasive surgery and non-surgical treatment for such tumors, including novel therapies and clinical trials.

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Ketyhole brain surgery


Keyhole Brain Tumor

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The term brain tumor encompasses growths that are both benign (non-cancerous) and malignant (cancerous). Brain tumors are usually classified into primary brain tumors (which include skull base tumors and pituitary tumors) and secondary (metastatic) brain tumors. Metastatic brain tumors arise from a cancer from elsewhere in the body. Skull base tumors arise in the bony structures and coverings of the brain and may be primary (arising in that specific location) or metastatic in origin (arising from a cancer elsewhere).

Primary brain tumors comprise a wide spectrum of benign and malignant neoplasms that may arise from the coverings of the brain (meningiomas, epidermoid and arachnoid cysts), from the brain itself (gliomas, astrocytomas, oligodendrogliomas, pineal tumors, lymphoma, hemangioblastoma), from the nerves that exit the brain (schwannomas, neurofibromas), from the pituitary gland and related structures (pituitary adenomas, craniopharyngiomas, Rathke’s cleft cysts), and from the skull base (meningiomas, chordomasschwannomas, olfactory neuroblastomas, sinus tumors). It is estimated that there are at least 60,000 primary brain tumors diagnosed annually in the United States.

Secondary brain tumors or metastatic brain tumors that arise from cancers elsewhere in the body are unfortunately common. They most often are seen in patients with cancers of the lung, breast, melanoma, colon, kidney and thyroid. It is estimated that at least 10-30% of cancer patients develop brain metastases. In total, it is estimated that approximately 200,000 patients per year are diagnosed with metastatic brain tumors in the United States, most of which come from tumors arising .

Given their location, brain tumors and skull base tumors may produce a variety of symptoms including headache, facial pain, seizures, visual loss, double vision, weakness, fatigue, numbness, difficulty walking, incoordination, confusion and personality changes.

Brain tumors and tumors of the skull base are best diagnosed by imaging studies, typically a magnetic resonance imaging (MRI) of the brain with gadolinium or a computer tomography (CT) scan of the brain. Sometimes focused MRIs of the pituitary region, temporal bones, internal auditory canals or orbits may be needed to obtain better anatomical detail of a tumor. Other tests may also be needed such as angiography (typically now performed as a CT angiogram or an MR angiogram), magnetic resonance spectroscopy, positron emission tomography (PET), visual field tests, audiograms or hormonal lab tests.

The optimal treatment of patients with brain tumors is dependent upon several factors including the tumor type, location, symptoms and overall health status of the patient. Therapy may include surgical removal, stereotactic radiosurgery or radiation therapy, chemotherapy and/or hormonal therapies.