A PNI Minute

A PNI Minute April 2024 | Dale Bredesen, MD, is an internationally recognized neurologist with specialty expertise in the mechanisms of neurodegenerative diseases. He is the senior director of Precision Brain Health at Pacific Neuroscience Institute®. His expertise in neurodegenerative diseases drives groundbreaking advancements in personalized treatment for Alzheimer's disease and other dementias. From decoding unique biomarkers to cognitive testing, Dr. Bredesen's work provides hope in tackling diseases of cognitive decline. pacificneuro.org/precision

MD Bio: https://www.pacificneuroscienceinstitute.org/people/sharma/

Moyamoya disease is a rare neurovascular condition that can affect both children and adults and is caused by progressive narrowing or blockage of the major blood vessels supplying the brain. Learn how experts at PNI treat this rare condition. Clinic: 818-847-6049 Consultation: https://www.pacificneuroscienceinstit... Dr. Adi Iyer: https://www.pacificneuroscienceinstit... More Information on Moyamoya Disease: https://www.pacificneuroscienceinstit...

Dr. Jennifer Bramen talks to ABC7 about how a low-carbohydrate diet could help slow the progression of Alzheimer’s disease. Research conducted at Pacific Neuroscience Institute shows promising results for Alzheimer’s patients who consumed fewer than 130 grams of net carbohydrates daily. The study published in Journal of Alzheimer’s Disease, suggests that this more liberal approach to carb consumption could provide options for those who would benefit from lower carbohydrate consumption but for one reason or another are unable to tolerate traditionally restrictive ketogenic diets. https://abc7.com/alzheimers-disease-n... Brain Health Center Consultation: 310-582-7641

At the Pacific Brain Health Center, geriatric psychiatrist Dr. David Merrill treats middle-aged and older adults. Transcranial Magnetic Stimulation (TMS) is a non-invasive methodology to treat depression taking advantage of the electrical nature of the brain to help modulate mood. Clinic consultation: 310-582-7641 https://www.pacificneuroscienceinstitute.org/brain-health/diagnostics-procedures/tms/ https://www.pacificneuroscienceinstitute.org/brain-health/schedule-a-consultation/ https://www.pacificneuroscienceinstitute.org/people/david-merrill/

Chordomas are rare tumors of the brain and spine that have limited surgical and neuro-oncological treatments. Learn about potential new treatment from a clinical trial published in 2023. Clinic: 310-829-8265 Appointments: https://www.pacificneuroscienceinstitute.org/brain-tumor/schedule-a-consultation/ Dr. Kesari: https://www.pacificneuroscienceinstitute.org/brain-tumor/people/santosh-kesari/ About Chordoma: https://www.pacificneuroscienceinstitute.org/brain-tumor/conditions/chordoma/

Sandra Narayanan, MD, Vascular Neurologist and Neurointerventional Surgeon at the Pacific Stroke and Neurovascular Center at Pacific Neuroscience Institute, explains the difference between hemorrhagic and ischemic stroke. The main difference between the two types of stroke is the underlying cause of the brain damage. In ischemic stroke, the damage is caused by a lack of blood supply due to a blood clot, while in hemorrhagic stroke, it is caused by bleeding into the brain tissue. Both types of stroke are medical emergencies and require immediate medical attention to prevent further damage and improve outcomes. https://www.pacificneuroscienceinstitute.org/people/sandra-narayanan/ https://www.pacificneuroscienceinstitute.org/stroke-neurovascular/conditions-and-treatments/stroke/

Cavernomas are a vascular mass made up of abnormal dilated blood vessels characterized by distended blood-filled “caverns.” Vessels of a cavernoma mass have a tendency to leak and bleed because they lack the proper junctions between neighboring cells as well as the necessary structural support from smooth muscle and the stretchable material (elastin) that normally supports regular blood vessels. While a new diagnosis of brain cavernoma can produce natural anxious responses in many patients, the most important thing to remember is that you are not alone — cavernomas can occur in as many as 1 out of every 200 people – and our team of experts is here to help you understand your condition and determine an optimal, personalized treatment plan for your needs. For more information: https://www.pacificneuroscienceinstitute.org/people/adi-iyer/ 818-847-6049 https://www.pacificneuroscienceinstitute.org/stroke-neurovascular/conditions-and-treatments/brain-vascular-malformation/cavernoma/

Five days after the birth of her second son, Nicky developed Bell's palsy, a facial paralysis affecting one side of the face. In a majority of people symptoms resolve with steroids and anti-viral treatments. The symptoms lingered for a year despite treatment at which point she was diagnosed with synkinesis, or abnormal facial nerve movement, which occurs about 10% of patients. Nicky was relieved as the diagnosis represented a path forward. Dr. Amit Kochhar at Pacific Neuroscience Institute has been working with Nicky for 2 years and she feels very grateful his expertise in treating synkinesis. Wilshire 310-477-5558 | Santa Monica 310-829-8701 https://www.pacificneuroscienceinstitute.org/eye-ent/facial-nerve-disorders/ Learn more: https://www.pacificneuroscienceinstitute.org/eye-ent/our-center/schedule-a-consultation-facial-nerve-disorders/

NBC News features Pacific Neuroscience Institute's Dr. Daniel Kelly & Dr. Keith Heinzerling, and filmmaker Louie Schwartzberg, and PNI's groundbreaking psychedelic-assisted clinical trial for alcohol use disorder which launched in March 2021. https://PacificTRIP.org Clinical trial for alcohol use disorder: 310-582-7611