Publications from our PNI Faculty

ResourcesPublications

Neurosurgery, neuro-oncology & endocrinology are rapidly evolving. Our PNI doctors are at the forefront of many developments in the treatment of brain, skull base and pituitary tumors. Some of our recent publications are provided below.

Conditions:

Brain Tumors, Skull Base Tumors and Pituitary Adenomas

Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis.

Marzese DM, Scolyer RA, Huynh JL, Huang SK, Hirose H, Chong KK, Kiyohara E, Wang J, Kawas NP, Donovan NC, Hata K, Wilmott JS, Murali R, Buckland ME, Shivalingam B, Thompson JF, Morton DL, Kelly DF, Hoon DS. Hum Mol Genet. 2014 Jan 1;23(1):226-38. Epub 2013 Sep 6. PMID:24014427

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Prospective validation of a patient-reported nasal quality-of-life tool for endonasal skull base surgery: The Anterior Skull Base Nasal Inventory-12.

Little AS, Kelly D, Milligan J, Griffiths C, Rosseau G, Prevedello DM, Carrau R, Jahnke H, Chaloner C, O'Leary J, Chapple K, Nakaji P, White WL.. J Neurosurg. 2013 May 10. [Epub ahead of print] PMID: 23662829.

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Neuronavigation in endonasal pituitary and skull base surgery using an autoregistration mask without head fixation: an assessment of accuracy and practicality.

McLaughlin N, Carrau, RL, Kassam AB, Kelly DF. J Neurol Surg A Cent Eur Neurosurg. 2012 Nov;73(6):351-7.

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Corticospinal tractography as a prognosticator for motor improvement after brainstem cavernoma resection.

McLaughlin N, Kelly DF: Br J Neurosurg. 2013 Feb;27(1):108-10.

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Side-cutting aspiration device for endoscopic and microscopic tumor removal.

McLaughlin N, Ditzel Filho LF, Prevedello DM, Kelly DF, Carrau RL, Kassam AB. J Neurol Surg B Skull Base. 2012 Feb;73(1):11-20.

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Endonasal management of sellar arachnoid cysts: simple cyst obliteration technique.

McLaughlin N, Vandergrift A, Ditzel Filho LF, Shahlaie K, Eisenberg AA, Carrau RL, Cohan P, Kelly DF. J Neurosurg. 2012 Apr;116(4):728-40.

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Transnasal, transfacial, anterior skull base resection of olfactory neuroblastoma.

Nabili V, Kelly DF, Fatemi N, St John M, Calcaterra TC, Abemayor E. Am J Otolaryngol. 2011 Jul-Aug;32(4):279-85.

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Management of Cushing’s disease after failed surgery–a review.

McLaughlin N, Kassam AB, Prevedello DM, Kelly DF. Can J Neurol Sci. 2011 Jan;38(1):12-21.

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The role of outcomes data for assessing the expertise of a pituitary surgeon.

Shahlaie K, McLaughlin N, Kassam AB, Kelly DF. Curr Opin Endocrinol Diabetes Obes. 2010 Aug;17(4):369-76.

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Endonasal transsphenoidal surgery and multimodality treatment for giant pituitary adenomas.

de Paiva Neto MA, Vandergrift A, Fatemi N, Gorgulho AA, Desalles AA, Cohan P, Wang C, Swerdloff R, Kelly DF. Clin Endocrinol (Oxf). 2010 Apr;72(4):512-9.

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Pituitary hormonal loss and recovery after transsphenoidal adenoma removal.

Fatemi N, Dusick JR, Mattozo C, McArthur DL, Cohan P, Boscardin J, Wang C, Swerdloff RS, Kelly DF. Neurosurgery. 2008 Oct;63(4):709-18; discussion 718-9.

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Primary sphenoid sinus neoplasms: a report of four cases with common clinical presentation treated with transsphenoidal surgery and adjuvant therapies.

Esposito F, Kelly DF, Vinters HV, DeSalles AA, Sercarz J, Gorgulhos AA. J Neurooncol. 2006 Feb;76(3):299-306.

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Vascular injury and transsphenoidal surgery.

Oskouian RJ, Kelly DF, Laws ER Jr. Front Horm Res. 2006;34:256-78.

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The extended direct endonasal transsphenoidal approach for nonadenomatous suprasellar tumors.

Dusick JR, Esposito F, Kelly DF, Cohan P, DeSalles A, Becker DP, Martin NA. J Neurosurg. 2005 May;102(5):832-41.

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Endonasal transsphenoidal transclival removal of prepontine epidermoid tumors: technical note.

Esposito F, Becker DP, Villablanca JP, Kelly DF. Neurosurgery. 2005 Apr;56(2 Suppl):E443; discussion E443.

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Symptomatic Rathke’s cleft cysts: a report of 24 cases.

Cohan P, Foulad A, Esposito F, Martin NA, Kelly DF. J Endocrinol Invest. 2004 Nov;27(10):943-8.

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Endonasal transsphenoidal approach for pituitary adenomas and other sellar lesions: an assessment of efficacy, safety, and patient impressions.

Zada G, Kelly DF, Cohan P, Wang C, Swerdloff R. J Neurosurg. 2003 Feb;98(2):350-8.

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Craniopharyngioma

The expanding role of the endonasal endoscopic approach in pituitary and skull base surgery: A 2014 perspective.

Lobo B, Heng A, Barkhoudarian G, Griffiths CF, Kelly DF. Surg Neurol Int. 2015 May 20; Review. PMID: 26015870

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Evolution of minimally invasive approaches to the sella and parasellar region.

Louis RG, Eisenberg A, Barkhoudarian G, Griffiths C, Kelly DF. Int Arch Otorhinolaryngol. 2014 Oct; PMID: 25992138

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The Supraorbital Endoscopic Approach for Tumors

Wilson DA, Duong H, Teo C, Kelly DF. World Neurosurg. 2013 Feb 5. [Epub ahead of print]

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Pituitary Centers of Excellence

McLaughlin N, Laws ER, Oyesiku NM, Katznelson L, Kelly DF. Neurosurgery. 2012 Aug 16. [Epub ahead of print]

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The supraorbital approach for recurrent or residual suprasellar tumors.

McLaughlin N, Ditzel Filho LF, Shahlaie K, Solari D, Kassam AB, Kelly DF. Minim Invasive Neurosurg. 2011 Aug;54(4):155-61.

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Endonasal vs supraorbital keyhole removal of craniopharyngiomas and tuberculum sellae meningiomas.

Fatemi N, Dusick JR, de Paiva Neto MA, Malkasian D, Kelly DF. Neurosurgery. 2009 May;64(5 Suppl 2):269-84; discussion 284-6.

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Pituitary function after endonasal surgery for nonadenomatous parasellar tumors: Rathke’s cleft cysts, craniopharyngiomas, and meningiomas.

Dusick JR, Fatemi N, Mattozo C, McArthur D, Cohan P, Wang C, Swerdloff RS, Kelly DF. Surg Neurol. 2008 Nov;70(5):482-90; discussion 490-1.

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The endonasal microscopic approach for pituitary adenomas and other parasellar tumors: a 10-year experience.

Fatemi N, Dusick JR, de Paiva Neto MA, Kelly DF. Neurosurgery. 2008 Oct;63(4 Suppl 2):244-56; discussion 256.

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The role of the endoscope in the transsphenoidal management of cystic lesions of the sellar region.

Cavallo LM, Prevedello D, Esposito F, Laws ER Jr, Dusick JR, Messina A, Jane JA Jr, Kelly DF, Cappabianca P. Neurosurg Rev. 2008 Jan;31(1):55-64; discussion 64.

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Graded repair of cranial base defects and cerebrospinal fluid leaks in transsphenoidal surgery.

Esposito F, Dusick JR, Fatemi N, Kelly DF. Neurosurgery. 2007 Apr;60(4 Suppl 2):295-303; discussion 303-4.

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Sellar Masses that Present with Severe Hyponatremia

Bordo G, Kelly K, McLaughlin N, Miyamoto S, Duong HT, Eisenberg A, Chaloner C, Cohan P, Barkhoudarian G, Kelly DF. Endocr Pract. 2014 Nov;20(11):1178-86. PMID: 25100360

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Chordoma

The expanding role of the endonasal endoscopic approach in pituitary and skull base surgery: A 2014 perspective.

Lobo B, Heng A, Barkhoudarian G, Griffiths CF, Kelly DF. Surg Neurol Int. 2015 May 20; Review. PMID: 26015870

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Evolution of minimally invasive approaches to the sella and parasellar region.

Louis RG, Eisenberg A, Barkhoudarian G, Griffiths C, Kelly DF. Int Arch Otorhinolaryngol. 2014 Oct; PMID: 25992138

Learn More

The endonasal microscopic approach for pituitary adenomas and other parasellar tumors: a 10-year experience.

Fatemi N, Dusick JR, de Paiva Neto MA, Kelly DF. Neurosurgery. 2008 Oct;63(4 Suppl 2):244-56; discussion 256.

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Endonasal microscopic removal of clival chordomas.

Fatemi N, Dusick JR, Gorgulho AA, Mattozo CA, Moftakhar P, De Salles AA, Kelly DF. Surg Neurol. 2008 Apr;69(4):331-8.

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Role of Endoscopic Skull Base and Keyhole Surgery for Pituitary and Parasellar Tumors Impacting Vision

Kelly DF, Griffiths CF, Takasumi Y, Rhee J, Barkhoudarian G, Krauss HR. J Neuroophthalmol. 2015 Dec;35(4):335-41. PMID: 26576016

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Glioma, GBM Astrocytoma – Medical Therapies, Tumor Genetic Profiling

Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.

Stupp R, Taillibert S, Kanner AA, Kesari S, Steinberg DM, Toms SA, Taylor LP, Lieberman F, Silvani A, Fink KL, Barnett GH, Zhu JJ, Henson JW, Engelhard HH, Chen TC, Tran DD, Sroubek J, Tran ND, Hottinger AF, Landolfi J, Desai R, Caroli M, Kew Y, Honnorat J, Idbaih A, Kirson ED, Weinberg U, Palti Y, Hegi ME, Ram Z. JAMA. 2015 Dec 15;314(23):2535-2543.

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PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation: A Randomized Phase II Study: BrUOG 244

Elinzano H, Glantz M, Mrugala M, Kesari S, Piccioni DE, Kim L, Pan E, Yunus S, Coyle T, Timothy K, Evans D, Mantripragada K, Boxerman J, DiPetrillo T, Donahue JE, Hebda N, Mitchell KM, Rosati KL, Safran H. Am J Clin Oncol. 2015 Dec 9.

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Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma.

Tsigelny IF, Mukthavaram R, Kouznetsova VL, Chao Y, Babic I, Nurmemmedov E, Pastorino S, Jiang P, Calligaris D, Agar N, Scadeng M, Pingle SC, Wrasidlo W, Makale MT, Kesari S. Oncotarget. 2015 Oct 30.

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A randomized phase I/II study of ABT-888 in combination with temozolomide in recurrent temozolomide resistant glioblastoma: an NRG oncology RTOG group study.

Robins HI, Zhang P, Gilbert MR, Chakravarti A, de Groot JF, Grimm SA, Wang F, Lieberman FS, Krauze A, Trotti AM, Mohile N, Kee AY, Colman H, Cavaliere R, Kesari S, Chmura SJ, Mehta M. J Neurooncol. 2015 Oct 27.

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Effect of the JAK2/STAT3 inhibitor SAR317461 on human glioblastoma tumorspheres

Mukthavaram R, Ouyang X, Saklecha R, Jiang P, Nomura N, Pingle SC, Guo F, Makale M, Kesari S. J Transl Med. 2015 Aug 18;13:269.

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Molecular profiling of gliomas: potential therapeutic implications

Alentorn A, Duran-Peña A, Pingle SC, Piccioni DE, Idbaih A, Kesari S. Expert Rev Anticancer Ther. 2015 Aug;15(8):955-62.

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Plexin-B2 promotes invasive growth of malignant glioma

Le AP, Huang Y, Pingle SC, Kesari S, Wang H, Yong RL, Zou H, Friedel RH. Oncotarget. 2015 Mar 30;6(9):7293-304.

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Glucose-corrected standardized uptake value in the differentiation of high-grade glioma versus post-treatment changes

Nozawa A, Rivandi AH, Kanematsu M, Hoshi H, Piccioni D, Kesari S, Hoh CK. Nucl Med Commun. 2015 Jun;36(6):573-81.

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Hierarchical control of coherent gene clusters defines the molecular mechanisms of glioblastoma

Tsigelny IF, Kouznetsova VL, Jiang P, Pingle SC, Kesari S. Mol Biosyst. 2015 Apr;11(4):1012-28.

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Phase 2 study of CT-322, a targeted biologic inhibitor of VEGFR-2 based on a domain of human fibronectin, in recurrent glioblastoma

Schiff D, Kesari S, de Groot J, Mikkelsen T, Drappatz J, Coyle T, Fichtel L, Silver B, Walters I, Reardon D. Invest New Drugs. 2015 Feb;33(1):247-53.

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Retrospective analysis of safety and feasibility of a 3 days on/11 days off temozolomide dosing regimen in recurrent adult malignant gliomas

van Vugt VA, Piccioni DE, Brown BD, Brown T, Saria MG, Juarez T, Kesari S. CNS Oncol. 2014 Jul;3(4):257-65.

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Prostate specific membrane antigen (PSMA) expression in primary gliomas and breast cancer brain metastases

Nomura N, Pastorino S, Jiang P, Lambert G, Crawford JR, Gymnopoulos M, Piccioni D, Juarez T, Pingle SC, Makale M, Kesari S. Cancer Cell Int. 2014 Mar 20;14(1):26.

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Sellar and supra-sellar glioblastoma masquerading as a pituitary macroadenoma

Mahta A, Buhl R, Huang H, Jansen O, Kesari S, Ulmer S. Neurol Sci. 2013 Apr;34(4):605-7. PMID: 22569569

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Cell phones and glioma risk: a review of the evidence

Corle C, Makale M, Kesari S. J Neurooncol. 2012 Jan;106(1):1-13. PMID: 21853424

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Corticosteroids in brain cancer patients: benefits and pitfalls

Dietrich J, Rao K, Pastorino S, Kesari S. Expert Rev Clin Pharmacol. 2011 Mar;4(2):233-42. PMID: 21666852

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Leptomeningeal Brain Metastasis

Leptomeningeal metastasis in breast cancer – a systematic review

Scott BJ, Oberheim-Bush NA, Kesari S. Oncotarget. 2015 Nov 2.

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A phase I trial of high dose gefitinib for patients with leptomeningeal metastases from non-small cell lung cancer

Jackman DM, Cioffredi LA, Jacobs L, Sharmeen F, Morse LK, Lucca J, Plotkin SR, Marcoux PJ, Rabin MS, Lynch TJ, Johnson BE, Kesari S. Oncotarget. 2015 Feb 28;6(6):4527-36.

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Concurrent intrathecal methotrexate and liposomal cytarabine for leptomeningeal metastasis from solid tumors: a retrospective cohort study

Scott BJ, van Vugt VA, Rush T, Brown T, Chen CC, Carter BS, Schwab R, Fanta P, Helsten T, Bazhenova L, Parker B, Pingle S, Saria MG, Brown BD, Piccioni DE, Kesari S. J Neurooncol. 2014 Sep;119(2):361-8.

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Novel approaches to treating leptomeningeal metastases

Grewal J, Saria MG, Kesari S. J Neurooncol. 2012 Jan;106(2):225-34. PMID: 21874597

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Durable remission of leptomeningeal metastases from hormone-responsive prostate cancer

Zhang M, Mahta A, Kim RY, Akar S, Kesari S. Med Oncol. 2012 Jun;29(2):806-8 PMID: 21424585

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Meningioma

The expanding role of the endonasal endoscopic approach in pituitary and skull base surgery: A 2014 perspective.

Lobo B, Heng A, Barkhoudarian G, Griffiths CF, Kelly DF. Surg Neurol Int. 2015 May 20; Review. PMID: 26015870

Learn More

Evolution of minimally invasive approaches to the sella and parasellar region.

Louis RG, Eisenberg A, Barkhoudarian G, Griffiths C, Kelly DF. Int Arch Otorhinolaryngol. 2014 Oct; PMID: 25992138

Learn More

The Supraorbital Endoscopic Approach for Tumors

Wilson DA, Duong H, Teo C, Kelly DF. World Neurosurg. 2013 Feb 5. [Epub ahead of print]

Learn More

The endonasal microscopic approach for pituitary adenomas and other parasellar tumors: a 10-year experience.

Fatemi N, Dusick JR, de Paiva Neto MA, Kelly DF. Neurosurgery. 2008 Oct;63(4 Suppl 2):244-56; discussion 256.

Learn More

The role of the endoscope in the transsphenoidal management of cystic lesions of the sellar region.

Cavallo LM, Prevedello D, Esposito F, Laws ER Jr, Dusick JR, Messina A, Jane JA Jr, Kelly DF, Cappabianca P. Neurosurg Rev. 2008 Jan;31(1):55-64; discussion 64.

Learn More

Graded repair of cranial base defects and cerebrospinal fluid leaks in transsphenoidal surgery.

Esposito F, Dusick JR, Fatemi N, Kelly DF. Neurosurgery. 2007 Apr;60(4 Suppl 2):295-303; discussion 303-4.

Learn More

Endonasal Endoscopic Management of Parasellar and Cavernous Sinus Meningiomas

Lobo B, Zhang X, Barkhoudarian G, Griffiths CF, Kelly DF. Neurosurg Clin N Am. 2015 Jul;26(3):389-401. doi: 10.1016/j.nec.2015.03.004. Epub 2015 May 7. Review. PMID: 26141358

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Role of Endoscopic Skull Base and Keyhole Surgery for Pituitary and Parasellar Tumors Impacting Vision

Kelly DF, Griffiths CF, Takasumi Y, Rhee J, Barkhoudarian G, Krauss HR. J Neuroophthalmol. 2015 Dec;35(4):335-41. PMID: 26576016

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Radiation-associated meningiomas in children: clinical, pathological, and cytogenetic characteristics with a critical review of the literature

Elbabaa SK, Gokden M, Crawford JR, Kesari S, Saad AG. J Neurosurg Pediatr. 2012 Oct;10(4):281-90 PMID: 22900483

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Metastatic Brain Tumor

Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis.

Marzese DM, Scolyer RA, Huynh JL, Huang SK, Hirose H, Chong KK, Kiyohara E, Wang J, Kawas NP, Donovan NC, Hata K, Wilmott JS, Murali R, Buckland ME, Shivalingam B, Thompson JF, Morton DL, Kelly DF, Hoon DS. Hum Mol Genet. 2014 Jan 1;23(1):226-38. Epub 2013 Sep 6. PMID:24014427

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Supraorbital Eyebrow Craniotomy for Removal of Intraaxial Frontal Brain Tumors.

Ditzel Filho LF, McLaughlin N, Bresson D, Solari D, Kassam AB, Kelly DF.: A Technical Note. World Neurosurg. 2013 Jan 23. [Epub ahead of print]

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The Supraorbital Endoscopic Approach for Tumors

Wilson DA, Duong H, Teo C, Kelly DF. World Neurosurg. 2013 Feb 5. [Epub ahead of print]

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Endoscopic and Gravity-Assisted Resection of Medial Temporo-occipital Lesions Through a Supracerebellar Transtentorial Approach: Technical Notes With Case Illustrations

Villanueva P, Louis RG, Cutler AR, Wei H, Sale D, Duong HT, Barkhoudarian G, Kelly DF. Neurosurgery. 2015 Aug 14. PMID: 26280113

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Epigenomic landscape of melanoma progression to brain metastasis: unexplored therapeutic alternatives

Marzese DM, Witz IP, Kelly DF, Hoon DS. Epigenomics. 2015 Dec 7. [Epub ahead of print] PMID: 26638944

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Brain metastasis is predetermined in early stages of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome

Marzese DM, Liu M, Huynh JL, Hirose H, Donovan NC, Huynh KT, Kiyohara E, Chong K, Cheng D, Tanaka R, Wang J, Morton DL, Barkhoudarian G, Kelly DF, Hoon DS. Pigment Cell Melanoma Res. 2015 Jan;28(1):82-93. doi: 10.1111/pcmr.12307. Epub 2014 Sep 30. PMID: 25169209

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DNA methylation and gene deletion analysis of brain metastases in melanoma patients identifies mutually exclusive molecular alterations

Marzese DM, Scolyer RA, Roqué M, Vargas-Roig LM, Huynh JL, Wilmott JS, Murali R, Buckland ME, Barkhoudarian G, Thompson JF, Morton DL, Kelly DF, Hoon DS.Neuro Oncol. 2014 Nov;16(11):1499-509. PMID: 24968695

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Strategies for overcoming the blood-brain barrier for the treatment of brain metastases

Hu J, Kesari S. CNS Oncol. 2013 Jan;2(1):87-98. PMID: 25054359

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Current Perspectives in the Management of Brain Metastases

Saria MG, Piccioni D, Carter J, Orosco H, Turpin T, Kesari S. Clin J Oncol Nurs. 2015 Aug;19(4):475-9. PMID: 26207714

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Pituitary Adenoma

Impact of selective pituitary gland incision or resection on hormonal function after adenoma or cyst resection.

Barkhoudarian G, Cutler AR, Yost S, Lobo B, Eisenberg A, Kelly DF. Pituitary. 2015 Jun 27.
PMID: 26115709

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Predictors of sinonasal quality of life and nasal morbidity after fully endoscopic transsphenoidal surgery.

Little AS, Kelly D, Milligan J, Griffiths C, Prevedello DM, Carrau RL, Rosseau G, Barkhoudarian G, Otto BA, Jahnke H, Chaloner C, Jelinek KL, Chapple K, White WL. J Neurosurg. 2015 Jun; Epub 2015 Apr 3. PMID: 25839931

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Comparison of sinonasal quality of life and health status in patients undergoing microscopic and endoscopic transsphenoidal surgery for pituitary lesions: a prospective cohort study.

Little AS, Kelly DF, Milligan J, Griffiths C, Prevedello DM, Carrau RL, Rosseau G, Barkhoudarian G, Jahnke H, Chaloner C, Jelinek KL, Chapple K, White WL. J Neurosurg. 2015 Apr 17, PMID: 25884256

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The expanding role of the endonasal endoscopic approach in pituitary and skull base surgery: A 2014 perspective.

Lobo B, Heng A, Barkhoudarian G, Griffiths CF, Kelly DF. Surg Neurol Int. 2015 May 20; Review. PMID: 26015870

Learn More

Evolution of minimally invasive approaches to the sella and parasellar region.

Louis RG, Eisenberg A, Barkhoudarian G, Griffiths C, Kelly DF. Int Arch Otorhinolaryngol. 2014 Oct; PMID: 25992138

Learn More

Chemotherapy-induced regression of an adrenocorticotropin-secreting pituitary carcinoma accompanied by secondary adrenal insufficiency.

Cornell RF, Kelly DF, Bordo G, Carroll TB, Duong HT, Kim J, Takasumi Y, Thomas JP, Wong YL, Findling JW. Case Rep Endocrinol. Epub 2013 Dec 22. PMID: 24455332

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The value of endoscopy for maximizing tumor removal in endonasal transsphenoidal pituitary adenoma surgery.

McLaughlin N, Eisenberg A, Cohan P, Chaloner C, Kelly DF. J Neurosurgery. 2013 Mar; 118(3):613-20.

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Pituitary Centers of Excellence

McLaughlin N, Laws ER, Oyesiku NM, Katznelson L, Kelly DF. Neurosurgery. 2012 Aug 16. [Epub ahead of print]

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Early morning cortisol levels as predictors of short and long-term adrenal function after endonasal transsphenoidal surgery for pituitary adenomas and Rathke’s cleft cysts.

McLaughlin N, Cohan P, Barnett P, Eisenberg A, Chaloner C, Kelly DF. World Neurosurg. 2012 Aug 14. [Epub ahead of print]

Learn More

Endonasal transsphenoidal surgery and multimodality treatment for giant pituitary adenomas.

de Paiva Neto MA, Vandergrift A, Fatemi N, Gorgulho AA, Desalles AA, Cohan P, Wang C, Swerdloff R, Kelly DF. Clin Endocrinol (Oxf). 2010 Apr;72(4):512-9.

Learn More

The endonasal microscopic approach for pituitary adenomas and other parasellar tumors: a 10-year experience.

Fatemi N, Dusick JR, de Paiva Neto MA, Kelly DF. Neurosurgery. 2008 Oct;63(4 Suppl 2):244-56; discussion 256.

Learn More

The role of the endoscope in the transsphenoidal management of cystic lesions of the sellar region.

Cavallo LM, Prevedello D, Esposito F, Laws ER Jr, Dusick JR, Messina A, Jane JA Jr, Kelly DF, Cappabianca P. Neurosurg Rev. 2008 Jan;31(1):55-64; discussion 64.

Learn More

Avoidance of carotid artery injuries in transsphenoidal surgery with the Doppler probe and micro-hook blades.

Dusick JR, Esposito F, Malkasian D, Kelly DF. Neurosurgery. 2007 Apr;60(4 Suppl 2):322-8; discussion 328-9.

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Graded repair of cranial base defects and cerebrospinal fluid leaks in transsphenoidal surgery.

Esposito F, Dusick JR, Fatemi N, Kelly DF. Neurosurgery. 2007 Apr;60(4 Suppl 2):295-303; discussion 303-4.

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Transsphenoidal surgery for Cushing’s disease: a review of success rates, remission predictors, management of failed surgery, and Nelson’s Syndrome.

Kelly DF. Neurosurg Focus. 2007;23(3):E5.

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Suboptimal sphenoid and sellar exposure: a consistent finding in patients treated with repeat transsphenoidal surgery for residual endocrine-inactive macroadenomas.

Mattozo CA, Dusick JR, Esposito F, Mora H, Cohan P, Malkasian D, Kelly DF. Neurosurgery. 2006 May;58(5):857-65; discussion 857-65.

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Endonasal transsphenoidal surgery: the patient’s perspective-survey results from 259 patients.

Dusick JR, Esposito F, Mattozo CA, Chaloner C, McArthur DL, Kelly DF. Surg Neurol. 2006 Apr;65(4):332-41, discussion 341-2.

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Clinical review: Early morning cortisol levels as a predictor of remission after transsphenoidal surgery for Cushing’s disease.

Esposito F, Dusick JR, Cohan P, Moftakhar P, McArthur D, Wang C, Swerdloff RS, Kelly DF. J Clin Endocrinol Metab. 2006 Jan;91(1):7-13.

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Sellar Masses that Present with Severe Hyponatremia

Bordo G, Kelly K, McLaughlin N, Miyamoto S, Duong HT, Eisenberg A, Chaloner C, Cohan P, Barkhoudarian G, Kelly DF. Endocr Pract. 2014 Nov;20(11):1178-86. PMID: 25100360

Learn More

Role of Endoscopic Skull Base and Keyhole Surgery for Pituitary and Parasellar Tumors Impacting Vision

Kelly DF, Griffiths CF, Takasumi Y, Rhee J, Barkhoudarian G, Krauss HR. J Neuroophthalmol. 2015 Dec;35(4):335-41. PMID: 26576016

Learn More

Rathke’s Cleft Cyst

Impact of selective pituitary gland incision or resection on hormonal function after adenoma or cyst resection.

Barkhoudarian G, Cutler AR, Yost S, Lobo B, Eisenberg A, Kelly DF. Pituitary. 2015 Jun 27.
PMID: 26115709

Learn More

The expanding role of the endonasal endoscopic approach in pituitary and skull base surgery: A 2014 perspective.

Lobo B, Heng A, Barkhoudarian G, Griffiths CF, Kelly DF. Surg Neurol Int. 2015 May 20; Review. PMID: 26015870

Learn More

Pituitary Centers of Excellence

McLaughlin N, Laws ER, Oyesiku NM, Katznelson L, Kelly DF. Neurosurgery. 2012 Aug 16. [Epub ahead of print]

Learn More

Early morning cortisol levels as predictors of short and long-term adrenal function after endonasal transsphenoidal surgery for pituitary adenomas and Rathke’s cleft cysts.

McLaughlin N, Cohan P, Barnett P, Eisenberg A, Chaloner C, Kelly DF. World Neurosurg. 2012 Aug 14. [Epub ahead of print]

Learn More

The role of outcomes data for assessing the expertise of a pituitary surgeon.

Shahlaie K, McLaughlin N, Kassam AB, Kelly DF. Curr Opin Endocrinol Diabetes Obes. 2010 Aug;17(4):369-76.

Learn More

Pituitary function after endonasal surgery for nonadenomatous parasellar tumors: Rathke’s cleft cysts, craniopharyngiomas, and meningiomas.

Dusick JR, Fatemi N, Mattozo C, McArthur D, Cohan P, Wang C, Swerdloff RS, Kelly DF. Surg Neurol. 2008 Nov;70(5):482-90; discussion 490-1.

Learn More

The endonasal microscopic approach for pituitary adenomas and other parasellar tumors: a 10-year experience.

Fatemi N, Dusick JR, de Paiva Neto MA, Kelly DF. Neurosurgery. 2008 Oct;63(4 Suppl 2):244-56; discussion 256.

Learn More

The role of the endoscope in the transsphenoidal management of cystic lesions of the sellar region.

Cavallo LM, Prevedello D, Esposito F, Laws ER Jr, Dusick JR, Messina A, Jane JA Jr, Kelly DF, Cappabianca P. Neurosurg Rev. 2008 Jan;31(1):55-64; discussion 64.

Learn More

Graded repair of cranial base defects and cerebrospinal fluid leaks in transsphenoidal surgery.

Esposito F, Dusick JR, Fatemi N, Kelly DF. Neurosurgery. 2007 Apr;60(4 Suppl 2):295-303; discussion 303-4.

Learn More

Symptomatic Rathke’s cleft cysts: a report of 24 cases.

Cohan P, Foulad A, Esposito F, Martin NA, Kelly DF. J Endocrinol Invest. 2004 Nov;27(10):943-8.

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Sellar Masses that Present with Severe Hyponatremia

Bordo G, Kelly K, McLaughlin N, Miyamoto S, Duong HT, Eisenberg A, Chaloner C, Cohan P, Barkhoudarian G, Kelly DF. Endocr Pract. 2014 Nov;20(11):1178-86. PMID: 25100360

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Brain Trauma and Pituitary Failure

Prevalence of pituitary hormone dysfunction, metabolic syndrome and impaired quality of life in retired professional football players: a prospective study.

Kelly DF, Chaloner C, Evans D, Matthews A, Cohan P, Wang C, Swerdloff R, Sim MS, Lee J, Wright MJ, Kernan CL, Barkhoudarian G, Yuen K, Guskiewicz KK. J Neurotrauma. 2014 Feb 19. [Epub ahead of print]

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Pathophysiology of hypopituitarism in the setting of brain injury.

Dusick JR, Wang C, Cohan P, Swerdloff R, Kelly DF. Pituitary. 2012 Mar;15(1):2-9.

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Chronic hypopituitarism after traumatic brain injury: risk assessment and relationship to outcome.

Bavisetty S, Bavisetty S, McArthur DL, Dusick JR, Wang C, Cohan P, Boscardin WJ, Swerdloff R, Levin H, Chang DJ, Muizelaar JP, Kelly DF. Neurosurgery. 2008 May;62(5):1080-93; discussion 1093-4.

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Neurobehavioral and quality of life changes associated with growth hormone insufficiency after complicated mild, moderate, or severe traumatic brain injury.

Kelly DF, McArthur DL, Levin H, Swimmer S, Dusick JR, Cohan P, Wang C, Swerdloff R. J Neurotrauma. 2006 Jun;23(6):928-42.

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Acute secondary adrenal insufficiency after traumatic brain injury: a prospective study.

Cohan P, Wang C, McArthur DL, Cook SW, Dusick JR, Armin B, Swerdloff R, Vespa P, Muizelaar JP, Cryer HG, Christenson PD, Kelly DF. Crit Care Med. 2005 Oct;33(10):2358-66

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Hypopituitarism following traumatic brain injury and aneurysmal subarachnoid hemorrhage: a preliminary report.

Kelly DF, Gonzalo IT, Cohan P, Berman N, Swerdloff R, Wang C. J Neurosurg. 2000 Nov;93(5):743-52.

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Treatment Approaches & Novel Therapies:

Biotherapy/Immunotherapy/Vaccines for Brain Cancer

Cancer anti-angiogenesis vaccines: Is the tumor vasculature antigenically unique?

Wagner SC, Ichim TE, Ma H, Szymanski J, Perez JA, Lopez J, Bogin V, Patel AN, Marincola FM, Kesari S. J Transl Med. 2015 Oct 29;13:340.

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Overcoming tumor immune evasion with an unique arbovirus

Lyday B, Chen T, Kesari S, Minev B. J Transl Med. 2015 Jan 16;13:3.

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Induction of tumor inhibitory anti-angiogenic response through immunization with interferon Gamma primed placental endothelial cells: ValloVax™

Ichim TE, Li S, Ma H, Yurova YV, Szymanski JS, Patel AN, Kesari S, Min WP, Wagner SC. J Transl Med. 2015 Mar 14;13:90.

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Bevacizumab: radiation combination produces restricted diffusion on brain MRI

Hesselink JR, Barkovich MJ, Seibert TM, Farid N, Muller KA, Murphy KT, Kesari S. CNS Oncol. 2014;3(5):329-35.

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Chemotherapy & Immunotherapy for Pituitary Tumors

Chemotherapy-induced regression of an adrenocorticotropin-secreting pituitary carcinoma accompanied by secondary adrenal insufficiency.

Cornell RF, Kelly DF, Bordo G, Carroll TB, Duong HT, Kim J, Takasumi Y, Thomas JP, Wong YL, Findling JW. Case Rep Endocrinol. Epub 2013 Dec 22. PMID: 24455332

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Drug Development

Nanoparticles: Recovery of Drug Delivery Nanoparticles from Human Plasma Using an Electrokinetic Platform Technology

Ibsen S, Sonnenberg A, Schutt C, Mukthavaram R, Yeh Y, Ortac I, Manouchehri S, Kesari S, Esener S, Heller MJ. Small. 2015 Oct;11(38):4990.

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Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics

Kato S, Schwaederle M, Daniels GA, Piccioni D, Kesari S, Bazhenova L, Shimabukuro K, Parker BA, Fanta P, Kurzrock R. Cell Cycle. 2015;14(8):1252-9.

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Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction

Fogal V, Babic I, Chao Y, Pastorino S, Mukthavaram R, Jiang P, Cho YJ, Pingle SC, Crawford JR, Piccioni DE, Kesari S. Oncotarget. 2015 Jan 20;6(2):1157-70.

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A novel bioavailable BH3 mimetic efficiently inhibits colon cancer via cascade effects of mitochondria

Wang X, Zhang C, Yan X, Lan B, Wang J, Wei C, Cao X, Wang R, Yao J, Zhou T, Zhou M, Liu Q, Jiang B, Jiang P, Kesari S, Lin X, Guo F. Clin Cancer Res. 2015 Oct 29

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In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells

Jiang P, Mukthavaram R, Chao Y, Nomura N, Bharati IS, Fogal V, Pastorino S, Teng D, Cong X, Pingle SC, Kapoor S, Shetty K, Aggrawal A, Vali S, Abbasi T, Chien S, Kesari S. Br J Cancer. 2014 Oct 14;111(8):1562-71.

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Targeting and depletion of circulating leukocytes and cancer cells by lipophilic antibody-modified erythrocytes

Mukthavaram R, Shi G, Kesari S, Simberg D. J Control Release. 2014 Jun 10;183:146-53.

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Novel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugs

Jiang P, Mukthavaram R, Chao Y, Bharati IS, Fogal V, Pastorino S, Cong X, Nomura N, Gallagher M, Abbasi T, Vali S, Pingle SC, Makale M, Kesari S. J Transl Med. 2014 Jan 17;12:13.

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PTEN status mediates 2ME2 anti-tumor efficacy in preclinical glioblastoma models: role of HIF1α suppression

Muh CR, Joshi S, Singh AR, Kesari S, Durden DL, Makale MT. J Neurooncol. 2014 Jan;116(1):89-97.

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Drug Development for Brain Cancer

Nanoparticles: Recovery of Drug Delivery Nanoparticles from Human Plasma Using an Electrokinetic Platform Technology

Ibsen S, Sonnenberg A, Schutt C, Mukthavaram R, Yeh Y, Ortac I, Manouchehri S, Kesari S, Esener S, Heller MJ. Small. 2015 Oct;11(38):4990.

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Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics

Kato S, Schwaederle M, Daniels GA, Piccioni D, Kesari S, Bazhenova L, Shimabukuro K, Parker BA, Fanta P, Kurzrock R. Cell Cycle. 2015;14(8):1252-9.

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Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction

Fogal V, Babic I, Chao Y, Pastorino S, Mukthavaram R, Jiang P, Cho YJ, Pingle SC, Crawford JR, Piccioni DE, Kesari S. Oncotarget. 2015 Jan 20;6(2):1157-70.

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A novel bioavailable BH3 mimetic efficiently inhibits colon cancer via cascade effects of mitochondria

Wang X, Zhang C, Yan X, Lan B, Wang J, Wei C, Cao X, Wang R, Yao J, Zhou T, Zhou M, Liu Q, Jiang B, Jiang P, Kesari S, Lin X, Guo F. Clin Cancer Res. 2015 Oct 29

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In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells

Jiang P, Mukthavaram R, Chao Y, Nomura N, Bharati IS, Fogal V, Pastorino S, Teng D, Cong X, Pingle SC, Kapoor S, Shetty K, Aggrawal A, Vali S, Abbasi T, Chien S, Kesari S. Br J Cancer. 2014 Oct 14;111(8):1562-71.

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Endonasal Endoscopic Surgery

Impact of selective pituitary gland incision or resection on hormonal function after adenoma or cyst resection.

Barkhoudarian G, Cutler AR, Yost S, Lobo B, Eisenberg A, Kelly DF. Pituitary. 2015 Jun 27.
PMID: 26115709

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Predictors of sinonasal quality of life and nasal morbidity after fully endoscopic transsphenoidal surgery.

Little AS, Kelly D, Milligan J, Griffiths C, Prevedello DM, Carrau RL, Rosseau G, Barkhoudarian G, Otto BA, Jahnke H, Chaloner C, Jelinek KL, Chapple K, White WL. J Neurosurg. 2015 Jun; Epub 2015 Apr 3. PMID: 25839931

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Comparison of sinonasal quality of life and health status in patients undergoing microscopic and endoscopic transsphenoidal surgery for pituitary lesions: a prospective cohort study.

Little AS, Kelly DF, Milligan J, Griffiths C, Prevedello DM, Carrau RL, Rosseau G, Barkhoudarian G, Jahnke H, Chaloner C, Jelinek KL, Chapple K, White WL. J Neurosurg. 2015 Apr 17, PMID: 25884256

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The expanding role of the endonasal endoscopic approach in pituitary and skull base surgery: A 2014 perspective.

Lobo B, Heng A, Barkhoudarian G, Griffiths CF, Kelly DF. Surg Neurol Int. 2015 May 20; Review. PMID: 26015870

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Evolution of minimally invasive approaches to the sella and parasellar region.

Louis RG, Eisenberg A, Barkhoudarian G, Griffiths C, Kelly DF. Int Arch Otorhinolaryngol. 2014 Oct; PMID: 25992138

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The value of endoscopy for maximizing tumor removal in endonasal transsphenoidal pituitary adenoma surgery.

McLaughlin N, Eisenberg A, Cohan P, Chaloner C, Kelly DF. J Neurosurgery. 2013 Mar; 118(3):613-20.

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Neuronavigation in endonasal pituitary and skull base surgery using an autoregistration mask without head fixation: an assessment of accuracy and practicality.

McLaughlin N, Carrau, RL, Kassam AB, Kelly DF. J Neurol Surg A Cent Eur Neurosurg. 2012 Nov;73(6):351-7.

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Pituitary Centers of Excellence

McLaughlin N, Laws ER, Oyesiku NM, Katznelson L, Kelly DF. Neurosurgery. 2012 Aug 16. [Epub ahead of print]

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Early morning cortisol levels as predictors of short and long-term adrenal function after endonasal transsphenoidal surgery for pituitary adenomas and Rathke’s cleft cysts.

McLaughlin N, Cohan P, Barnett P, Eisenberg A, Chaloner C, Kelly DF. World Neurosurg. 2012 Aug 14. [Epub ahead of print]

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Endonasal management of sellar arachnoid cysts: simple cyst obliteration technique.

McLaughlin N, Vandergrift A, Ditzel Filho LF, Shahlaie K, Eisenberg AA, Carrau RL, Cohan P, Kelly DF. J Neurosurg. 2012 Apr;116(4):728-40.

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Management of Cushing’s disease after failed surgery–a review.

McLaughlin N, Kassam AB, Prevedello DM, Kelly DF. Can J Neurol Sci. 2011 Jan;38(1):12-21.

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The role of outcomes data for assessing the expertise of a pituitary surgeon.

Shahlaie K, McLaughlin N, Kassam AB, Kelly DF. Curr Opin Endocrinol Diabetes Obes. 2010 Aug;17(4):369-76.

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Endonasal transsphenoidal surgery and multimodality treatment for giant pituitary adenomas.

de Paiva Neto MA, Vandergrift A, Fatemi N, Gorgulho AA, Desalles AA, Cohan P, Wang C, Swerdloff R, Kelly DF. Clin Endocrinol (Oxf). 2010 Apr;72(4):512-9.

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Endonasal vs supraorbital keyhole removal of craniopharyngiomas and tuberculum sellae meningiomas.

Fatemi N, Dusick JR, de Paiva Neto MA, Malkasian D, Kelly DF. Neurosurgery. 2009 May;64(5 Suppl 2):269-84; discussion 284-6.

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Pituitary function after endonasal surgery for nonadenomatous parasellar tumors: Rathke’s cleft cysts, craniopharyngiomas, and meningiomas.

Dusick JR, Fatemi N, Mattozo C, McArthur D, Cohan P, Wang C, Swerdloff RS, Kelly DF. Surg Neurol. 2008 Nov;70(5):482-90; discussion 490-1.

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The endonasal microscopic approach for pituitary adenomas and other parasellar tumors: a 10-year experience.

Fatemi N, Dusick JR, de Paiva Neto MA, Kelly DF. Neurosurgery. 2008 Oct;63(4 Suppl 2):244-56; discussion 256.

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Pituitary hormonal loss and recovery after transsphenoidal adenoma removal.

Fatemi N, Dusick JR, Mattozo C, McArthur DL, Cohan P, Boscardin J, Wang C, Swerdloff RS, Kelly DF. Neurosurgery. 2008 Oct;63(4):709-18; discussion 718-9.

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Endonasal microscopic removal of clival chordomas.

Fatemi N, Dusick JR, Gorgulho AA, Mattozo CA, Moftakhar P, De Salles AA, Kelly DF. Surg Neurol. 2008 Apr;69(4):331-8.

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The role of the endoscope in the transsphenoidal management of cystic lesions of the sellar region.

Cavallo LM, Prevedello D, Esposito F, Laws ER Jr, Dusick JR, Messina A, Jane JA Jr, Kelly DF, Cappabianca P. Neurosurg Rev. 2008 Jan;31(1):55-64; discussion 64.

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Avoidance of carotid artery injuries in transsphenoidal surgery with the Doppler probe and micro-hook blades.

Dusick JR, Esposito F, Malkasian D, Kelly DF. Neurosurgery. 2007 Apr;60(4 Suppl 2):322-8; discussion 328-9.

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Graded repair of cranial base defects and cerebrospinal fluid leaks in transsphenoidal surgery.

Esposito F, Dusick JR, Fatemi N, Kelly DF. Neurosurgery. 2007 Apr;60(4 Suppl 2):295-303; discussion 303-4.

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Transsphenoidal surgery for Cushing’s disease: a review of success rates, remission predictors, management of failed surgery, and Nelson’s Syndrome.

Kelly DF. Neurosurg Focus. 2007;23(3):E5.

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Suboptimal sphenoid and sellar exposure: a consistent finding in patients treated with repeat transsphenoidal surgery for residual endocrine-inactive macroadenomas.

Mattozo CA, Dusick JR, Esposito F, Mora H, Cohan P, Malkasian D, Kelly DF. Neurosurgery. 2006 May;58(5):857-65; discussion 857-65.

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Endonasal Endoscopic Management of Parasellar and Cavernous Sinus Meningiomas

Lobo B, Zhang X, Barkhoudarian G, Griffiths CF, Kelly DF. Neurosurg Clin N Am. 2015 Jul;26(3):389-401. doi: 10.1016/j.nec.2015.03.004. Epub 2015 May 7. Review. PMID: 26141358

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Role of Endoscopic Skull Base and Keyhole Surgery for Pituitary and Parasellar Tumors Impacting Vision

Kelly DF, Griffiths CF, Takasumi Y, Rhee J, Barkhoudarian G, Krauss HR. J Neuroophthalmol. 2015 Dec;35(4):335-41. PMID: 26576016

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Imaging

Diffusion-weighted imaging in cancer: physical foundations and applications of restriction spectrum imaging

White NS, McDonald C, Farid N, Kuperman J, Karow D, Schenker-Ahmed NM, Bartsch H, Rakow-Penner R, Holland D, Shabaik A, Bjørnerud A, Hope T, Hattangadi-Gluth J, Liss M, Parsons JK, Chen CC, Raman S, Margolis D, Reiter RE, Marks L, Kesari S, Mundt AJ, Kane CJ, Carter BS, Bradley WG, Dale AM. Cancer Res. 2014 Sep 1;74(17):4638-52.

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Combining diffusion and perfusion differentiates tumor from bevacizumab-related imaging abnormality

Farid N, Almeida-Freitas DB, White NS, McDonald CR, Kuperman JM, Almutairi AA, Muller KA, VandenBerg SR, Kesari S, Dale AM. J Neurooncol. 2014 Dec;120(3):539-46.

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Minimally Invasive Keyhole Surgery

The expanding role of the endonasal endoscopic approach in pituitary and skull base surgery: A 2014 perspective.

Lobo B, Heng A, Barkhoudarian G, Griffiths CF, Kelly DF. Surg Neurol Int. 2015 May 20; Review. PMID: 26015870

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Evolution of minimally invasive approaches to the sella and parasellar region.

Louis RG, Eisenberg A, Barkhoudarian G, Griffiths C, Kelly DF. Int Arch Otorhinolaryngol. 2014 Oct; PMID: 25992138

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Supraorbital Eyebrow Craniotomy for Removal of Intraaxial Frontal Brain Tumors.

Ditzel Filho LF, McLaughlin N, Bresson D, Solari D, Kassam AB, Kelly DF.: A Technical Note. World Neurosurg. 2013 Jan 23. [Epub ahead of print]

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The Supraorbital Endoscopic Approach for Tumors

Wilson DA, Duong H, Teo C, Kelly DF. World Neurosurg. 2013 Feb 5. [Epub ahead of print]

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The value of endoscopy for maximizing tumor removal in endonasal transsphenoidal pituitary adenoma surgery.

McLaughlin N, Eisenberg A, Cohan P, Chaloner C, Kelly DF. J Neurosurgery. 2013 Mar; 118(3):613-20.

Learn More

Neuronavigation in endonasal pituitary and skull base surgery using an autoregistration mask without head fixation: an assessment of accuracy and practicality.

McLaughlin N, Carrau, RL, Kassam AB, Kelly DF. J Neurol Surg A Cent Eur Neurosurg. 2012 Nov;73(6):351-7.

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The supraorbital approach for recurrent or residual suprasellar tumors.

McLaughlin N, Ditzel Filho LF, Shahlaie K, Solari D, Kassam AB, Kelly DF. Minim Invasive Neurosurg. 2011 Aug;54(4):155-61.

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Endonasal transsphenoidal surgery and multimodality treatment for giant pituitary adenomas.

de Paiva Neto MA, Vandergrift A, Fatemi N, Gorgulho AA, Desalles AA, Cohan P, Wang C, Swerdloff R, Kelly DF. Clin Endocrinol (Oxf). 2010 Apr;72(4):512-9.

Learn More

Endonasal vs supraorbital keyhole removal of craniopharyngiomas and tuberculum sellae meningiomas.

Fatemi N, Dusick JR, de Paiva Neto MA, Malkasian D, Kelly DF. Neurosurgery. 2009 May;64(5 Suppl 2):269-84; discussion 284-6.

Learn More

Avoidance of carotid artery injuries in transsphenoidal surgery with the Doppler probe and micro-hook blades.

Dusick JR, Esposito F, Malkasian D, Kelly DF. Neurosurgery. 2007 Apr;60(4 Suppl 2):322-8; discussion 328-9.

Learn More

Graded repair of cranial base defects and cerebrospinal fluid leaks in transsphenoidal surgery.

Esposito F, Dusick JR, Fatemi N, Kelly DF. Neurosurgery. 2007 Apr;60(4 Suppl 2):295-303; discussion 303-4.

Learn More

Endonasal Endoscopic Management of Parasellar and Cavernous Sinus Meningiomas

Lobo B, Zhang X, Barkhoudarian G, Griffiths CF, Kelly DF. Neurosurg Clin N Am. 2015 Jul;26(3):389-401. doi: 10.1016/j.nec.2015.03.004. Epub 2015 May 7. Review. PMID: 26141358

Learn More

Role of Endoscopic Skull Base and Keyhole Surgery for Pituitary and Parasellar Tumors Impacting Vision

Kelly DF, Griffiths CF, Takasumi Y, Rhee J, Barkhoudarian G, Krauss HR. J Neuroophthalmol. 2015 Dec;35(4):335-41. PMID: 26576016

Learn More

Endoscopic and Gravity-Assisted Resection of Medial Temporo-occipital Lesions Through a Supracerebellar Transtentorial Approach: Technical Notes With Case Illustrations

Villanueva P, Louis RG, Cutler AR, Wei H, Sale D, Duong HT, Barkhoudarian G, Kelly DF. Neurosurgery. 2015 Aug 14. PMID: 26280113

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Endonasal transsphenoidal surgery and multimodality treatment for giant pituitary adenomas

de Paiva Neto MA, Vandergrift A, Fatemi N, Gorgulho AA, Desalles AA, Cohan P, Wang C, Swerdloff R, Kelly DF. Clin Endocrinol (Oxf). 2010 Apr;72(4):512-9.

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Precision Medicine

Molecular inimitability amongst tumors: implications for precision cancer medicine in the age of personalized oncology

Patel SP, Schwaederle M, Daniels GA, Fanta PT, Schwab RB, Shimabukuro KA, Kesari S, Piccioni DE, Bazhenova LA, Helsten TL, Lippman SM, Parker BA, Kurzrock R. Oncotarget. 2015 Oct 20;6(32):32602-9.

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Next generation sequencing demonstrates association between tumor suppressor gene aberrations and poor outcome in patients with cancer

Schwaederle M, Daniels GA, Piccioni DE, Kesari S, Fanta PT, Schwab RB, Shimabukuro KA, Parker BA, Kurzrock R. Cell Cycle. 2015;14(11):1730-7.

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